• King Henry VIII of England begins his suppression of the English monasteries.
• Genoa defeats and annexes Savona.
• Pope Clement VII conquers the city of Rimini
• Spanish conquistador Pánfilo de Narváez leads an expedition to conquer Florida. After a futile search for gold, he decides to head back to Mexico, but he and all his men are lost off the coast of Texas, except for Cabeza de Vaca, who spends the next several years wandering about the southern part of what is now the United States.
• Mughal emperor Babar orders the Rãmajanmasthãn Hindu temple at Ayodhya destroyed and replaced with the Babri Mosque, beginning a conflict over the site that rages to this day.
• Spain grants control of Tripoli to the Knights of Saint John.
• Baldassare Castiglione publishes his Il Libro del Cortegiano (The Book of the Courtier), a landmark treatise on Italian etiquette and social issues.
• Jon Aresson establishes the first Icelandic printing press at Holar.

These people were born in 1528:

• Japan's "13-day Shogun," Akechi Mitsuhide.
• Italian painter of the Venetian school Paolo Veronese.
• Portuguese dramatist and poet António Ferreira.
• French poet Remy Belleau.
• Italian mannerist painter Girolamo Muziano.

These people died in 1528:

• German engraver Albrecht Dürer
• Askia Muhammad I, the emperor of Songhai.
• Spanish conquistador Pánfilo de Narváez.
• Scottish Protestant martyr Patrick Hamilton.

1527 - 1528 - 1529

16th century